Misuse could be the intentional use, for therapeutic applications, of the drug by a person in a means aside from prescribed by a healthcare supplier or for whom it wasn't prescribed.

Lamotrigine Serum lamotrigine concentrations may very well be lowered, manufacturing a minimize in therapeutic results.

Store PERCOCET securely, from sight and access of youngsters, and in a place not obtainable by Many others, together with site visitors to the house.

Reserve concomitant prescribing to be used in sufferers for whom different treatment options are insufficient; Restrict dosages and durations for the minimal necessary; and follow sufferers for signs and symptoms of respiratory depression and sedation

Concomitant use of PERCOCET with CYP3A4 inducers or discontinuation of the CYP3A4 inhibitor could lessen oxycodone hydrochloride plasma concentrations, decrease opioid efficacy or, probably, cause a withdrawal syndrome in a very affected person who had produced Actual physical dependence to oxycodone hydrochloride.

Immediate discontinuation has also been affiliated with makes an attempt to discover other sources of opioid analgesics, which may be bewildered with drug-seeking for abuse.

Ahead of taking PERCOCET, notify your Health care company When you have a history of: Head injuries, seizures

The causal job of opioids within the syndrome of hypogonadism here is unfamiliar as the different healthcare, Bodily, Way of living, and psychological stressors that will impact gonadal hormone degrees haven't been adequately controlled for in studies executed thus far [see ADVERSE REACTIONS].

For the reason that respiratory despair may very well be increased than in any read more other case predicted, decrease the dosage of PERCOCET and/or even the muscle relaxant as essential.

Oxycodone may possibly cause side more info effects. Explain to your doctor if any of such indications, are extreme or do not go away:

Impairment of Fertility In scientific tests carried out by the National Toxicology Application, fertility assessments with acetaminophen are already completed in Swiss CD-1 mice by using a steady breeding review. There have been no effects on fertility parameters in mice consuming as much as one.seven times the MHDD of acetaminophen, determined by a human body area space comparison. Even though there was no effect on sperm motility or sperm density within the epididymis, there was a significant increase in the percentage of irregular sperm in mice consuming one.

Opioids are sought for nonmedical use and so are matter to diversion check here from respectable prescribed use. Take into consideration these threats when prescribing or dispensing PERCOCET. Procedures to scale back these hazards involve prescribing the drug from the smallest ideal quantity and advising the affected individual on thorough storage of the drug during the study course of cure and appropriate disposal of unused drug [see PRECAUTIONS; Information and facts for Sufferers/Caregivers].

Prolonged use throughout pregnancy can lead to neonatal opioid withdrawal syndrome, which may be everyday living-threatening Otherwise identified and addressed

Notice: This document contains side influence specifics of acetaminophen / oxycodone. click here Some dosage types mentioned on this web page may not use to your manufacturer identify Percocet.